Article No
RN007M
Anti-ELAVL1 (HuR) mAb
Anti-ELAVL1 (HuR) mAb
Antibodies Primary
Specifications
| Application | IP, RIA, WB |
| Article No | RN007M |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | C67-1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-ELAVL1 (HuR) mAb |
| Supplier | MBL |
| Isotype | IgG2a k |
| Notes | ELAVL1/HuR, like other ELAVL proteins, has a short N-terminal region followed by 2 RNA-binding motifs, a basic linker domain, and a third RNA-binding motif. The basic hinge region bears a novel nuclear shuttling sequence which is implicated in the nucleocytoplasmic HuR shuttling. Unlike its neuron-specific ELAV relatives (HuB, HuC and HuD), HuR itself is ubiquitously expressed. Structure-function analyses of HuR have shown that it binds to AU-rich mRNA sequences in the nucleus and may be involved in their nuclear export. |
| Product Type | Antibodies Primary |
| Research area | Epigenetics |
| Shipping Information | 4°C |
| Size | 200 µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat, hamster |
| Storage | -20°C |
| Substrate / Buffer | PBS containing 50% Glycerol (pH 7.2) |
| Technical Specifications | ELAVL1/HuR, like other ELAVL proteins, has a short N-terminal region followed by 2 RNA-binding motifs, a basic linker domain, and a third RNA-binding motif. The basic hinge region bears a novel nuclear shuttling sequence which is implicated in the nucleocytoplasmic HuR shuttling. Unlike its neuron-specific ELAV relatives (HuB, HuC and HuD), HuR itself is ubiquitously expressed. Structure-function analyses of HuR have shown that it binds to AU-rich mRNA sequences in the nucleus and may be involved in their nuclear export. |
| Product Page Updated | 2023-12-29T16:20:16.638Z |
