Article No
PM077
Anti-5-hydroxymethylcytosine (5hmC) pAb
Anti-5-hydroxymethylcytosine (5hmC) pAb
Antibodies Primary
Specifications
| Application | IP, WB |
| Article No | PM077 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Anti-5-hydroxymethylcytosine (5hmC) pAb |
| Supplier | MBL |
| Immunogen | BSA-conjugated 5-hydroxymethylcytidine |
| Isotype | Ig |
| Notes | DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC. |
| Product Type | Antibodies Primary |
| Research area | Epigenetics |
| Shipping Information | 4°C |
| Size | 100 µl |
| Source / Host | rabbit |
| Storage | -20°C |
| Substrate / Buffer | PBS/50% glycerol, pH 7.2 |
| Technical Specifications | DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC. |
| Product Page Updated | 2023-12-29T16:20:16.638Z |
