Article No
MEX004-6
Anti-CD326 (EpCAM) mAb-Biotin
Anti-CD326 (EpCAM) mAb-Biotin
Antibodies Primary
Specifications
| Application | FC, ELISA |
| Article No | MEX004-6 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | B8-4 |
| Clone Type | monoclonal |
| Concentration | B8-4 |
| Conjugation | Biotin |
| Description | Anti-CD326 (EpCAM) mAb-Biotin |
| Supplier | MBL |
| Immunogen | Recombinant human CD326 (EpCAM), Fc fusion protein |
| Isotype | IgG1 k |
| Notes | The epithelial cell adhesion molecule (EpCAM), also known as a CD326, is a transmembrane glycoprotein and first discovered on human colon carcinoma. In addition, EpCAM is defined as a monoclonal antibody AUA1-reactive cell surface antigen. This type I membrane protein is expressed only on epithelial cells and highly expressed on most carcinoma such as colorectal carcinoma and gastric cancer. EpCAM plays a role in cell-to-cell adhesion by regulating its own homophilic interaction in a Ca2+ independent manner. It is reported that tumor-derived circulating exosomes, called Extracellular Vesicles (EVs) or microvesicles, can be easily isolated using anti-EpCAM antibody bound magnetic beads, followed by various down-stream analyses such as sandwich immunoassay and RT-qPCR to elucidate the tumor-specific exosome surface protein profile and associated miRNA. |
| Product Type | Antibodies Primary |
| Research area | Epigenetics |
| Shipping Information | 4°C |
| Size | 50 µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Technical Specifications | The epithelial cell adhesion molecule (EpCAM), also known as a CD326, is a transmembrane glycoprotein and first discovered on human colon carcinoma. In addition, EpCAM is defined as a monoclonal antibody AUA1-reactive cell surface antigen. This type I membrane protein is expressed only on epithelial cells and highly expressed on most carcinoma such as colorectal carcinoma and gastric cancer. EpCAM plays a role in cell-to-cell adhesion by regulating its own homophilic interaction in a Ca2+ independent manner. It is reported that tumor-derived circulating exosomes, called Extracellular Vesicles (EVs) or microvesicles, can be easily isolated using anti-EpCAM antibody bound magnetic beads, followed by various down-stream analyses such as sandwich immunoassay and RT-qPCR to elucidate the tumor-specific exosome surface protein profile and associated miRNA. |
| Product Page Updated | 2023-12-29T16:20:16.638Z |
