Article No
LS-C96363-100
NCBI Number | 2015 |
Application | IHC |
Article No | LS-C96363-100 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | BM8 |
Clone Type | monoclonal |
Concentration | 0.2 mg/ml |
Conjugation | Biotin |
Description | EMR1 antibody LS-C96363 is a biotin-conjugated rat monoclonal antibody to mouse EMR1 (ADGRE1). Validated for IHC. |
Recommended Dilution | IHC-Fr (1:200) |
Supplier | LifeSpan Biosciences |
Entrez Gene ID | 2015 |
Gene Symbol | ADGRE1 |
Immunogen | Cultured macrophages. |
Isotype | IgG2a |
Notes | EMR1 antibody LS-C96363 is a biotin-conjugated rat monoclonal antibody to mouse EMR1 (ADGRE1). Validated for IHC. |
Alias Names | ADGRE1, EMR1 hormone receptor, F4/80, EGF-like module receptor 1, TM7LN3, EMR1 |
Product Type | Antibodies Primary |
Protocol | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
Purification | Affinity Purified |
Shipping Information | RT |
Size | 100 µg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | -20°C, 4°C |
Substrate / Buffer | Lyophilized from PBS, pH 7.2, 5 mg/ml BSA |
Technical Specifications | The antigen is a 125kD extracellular membrane protein sensitive to 2-mercaptoethanol. Antigen distribution: Isolated Cells: The antigen is expressed in vitro on over 80% of M-CSF stimulated bone marrow derived macrophages, after a few days of culture. It is absent from granulocytes, lymphocytes and thrombocytes. Tissue Sections: The antigen is detected on tissue fixed macrophages in all organs tested so far (spleen, lymph nodes, thymus, liver, skin) except lung. It is also present on Langerhans cells in the skin and Kupffer cells in the liver. In complete Freund's adjuvant induced granulomas, the antigen is expressed by inflammatory macrophages, but is absent from epitheloid cells. Specificity: Mouse: major subpopulation of resident tissue macrophages Other species: human heart macrophages |
Product Page Updated | 2024-04-12T12:29:59.363Z |