Article No
LS-C391622-100
Application | FC, IF, IHC |
Article No | LS-C391622-100 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | LAM03 |
Clone Type | monoclonal |
Concentration | 0.2 mg/ml |
Conjugation | Unconjugated |
Description | Human Lambda Light Chain antibody LS-C391622 is an unconjugated mouse monoclonal antibody. Validated for Flow, IF and IHC. |
Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (0.5 - 1 ug/ml) |
Supplier | LifeSpan Biosciences |
Immunogen | Purified human lambda light chain. |
Isotype | IgG1 k |
Notes | Human Lambda Light Chain antibody LS-C391622 is an unconjugated mouse monoclonal antibody. Validated for Flow, IF and IHC. |
Product Type | Antibodies Secondary |
Protocol | This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. The optimal dilution of the Lambda antibody for each application should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. |
Purification | Protein G Purified |
Shipping Information | RT |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Substrate / Buffer | 0.01% BSA, 0.05% sodium azide |
Technical Specifications | Human Lambda Light Chain |
Product Page Updated | 2024-04-12T09:20:06.597Z |