Article No
LS-C391154-100
CA9 / Carbonic Anhydrase IX
Carbonic Anhydrase IX antibody LS-C391154 is an unconjugated mouse monoclonal antibody to Carbonic Anhydrase IX (CA9) from human. It is reactive with human and horse. Validated for Flow, IF, IHC and WB.
Antibodies Primary
Specifications
| NCBI Number | 768 |
| Application | FC, IF, IHC, WB |
| Article No | LS-C391154-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | PN-15 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Carbonic Anhydrase IX antibody LS-C391154 is an unconjugated mouse monoclonal antibody to Carbonic Anhydrase IX (CA9) from human. It is reactive with human and horse. Validated for Flow, IF, IHC and WB. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (1 - 2 ug/ml), IHC-P (0.5 - 1 ug/ml), WB (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 768 |
| Gene Symbol | CA9 |
| Immunogen | The microsomal fraction of human renal cortical tissue homogenate. |
| Isotype | IgG2b k |
| Notes | Carbonic Anhydrase IX antibody LS-C391154 is an unconjugated mouse monoclonal antibody to Carbonic Anhydrase IX (CA9) from human. It is reactive with human and horse. Validated for Flow, IF, IHC and WB. |
| Alias Names | CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, Carbonic dehydratase, G250, MN, Membrane antigen MN, p54/58N, RCC-associated antigen G250, RCC-associated protein G250, Carbonic anhydrase 9, PMW1 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/CA9/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This mAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | horse/equine, human |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human CA9 / Carbonic Anhydrase IX |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
