Article No
LS-C390695-100
NCBI Number | 4586 |
Application | FC, IF, IHC |
Article No | LS-C390695-100 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | 1-13M1 |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Description | MUC5AC antibody LS-C390695 is an unconjugated mouse monoclonal antibody to MUC5AC from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC. |
Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (1 - 2 ug/ml), IHC-Fr (0.5 - 1 ug/ml) |
Supplier | LifeSpan Biosciences |
Entrez Gene ID | 4586 |
Gene Symbol | MUC5AC |
Immunogen | M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient. |
Isotype | IgG1 k |
Notes | MUC5AC antibody LS-C390695 is an unconjugated mouse monoclonal antibody to MUC5AC from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC. |
Alias Names | MUC5AC, Gastric mucin, Major airway glycoprotein, Muc5/5ac, Mucin-5AC, LeB, Lewis B blood group antigen, Tracheobronchial mucin, TBM, MUC-5AC, MUC5 |
Product Type | Antibodies Primary |
Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This mAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. mAb 1-13M1 pairs with mAb 9-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Optimal dilution of the MUC5AC antibody should be determined by the researcher. |
Purification | Protein G Purified |
Shipping Information | RT |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | chicken, cow/bovine, human, monkey, mouse, rabbit, rat |
Storage | 4°C |
Substrate / Buffer | Sterile Solution PBS |
Technical Specifications | Human MUC5AC |
Product Page Updated | 2024-04-12T09:20:06.597Z |