Article No
GTX34942
Specifications
| Application | FC, ICC, IF, IHC |
| Article No | GTX34942 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 57P06 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | p57 Kip2 antibody [57P06] |
| Supplier | GeneTex |
| Entrez Gene ID | 1028 |
| Gene Symbol | CDKN1C |
| Immunogen | Recombinant full-length human p57Kip2 protein |
| Isotype | IgG2b |
| Notes | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| Product Type | Antibodies Primary |
| Protocol | ICC/IF: 1-2µg/ml. IHC-P: 0.25-0.5µg/ml for 30 minutes at RT. FACS: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein A/G Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C, -80°C |
| UniProt Number | P49918 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
