Article No
GTX34166
Specifications
| Application | IHC |
| Article No | GTX34166 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 5h10 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Caspase 3 antibody [5H10] |
| Supplier | GeneTex |
| Entrez Gene ID | 836 |
| Gene Symbol | CASP3 |
| Immunogen | synthetic peptide derived from Caspase-3 at 20-100 aa. |
| Isotype | IgG1 |
| Notes | The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017] |
| Product Type | Antibodies Primary |
| Protocol | IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C, -80°C |
| UniProt Number | P42574 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
