Article No
GTX22722
Specifications
| Application | ChIP, EMSA, FC, ICC, IF, IHC, IP, WB |
| Article No | GTX22722 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 25A10.D6.D2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | NFAT1 antibody [25A10.D6.D2] |
| Supplier | GeneTex |
| Entrez Gene ID | 18019 |
| Gene Symbol | Nfatc2 |
| Immunogen | Synthetic peptide corresponding to residues A(51) I S S P S G L A Y P D D V L D Y G L(69) of mouse NFATc2-A, B and C isoforms. |
| Isotype | IgG1 |
| Notes | The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent. |
| Product Type | Antibodies Primary |
| Protocol | WB: 1 µg/ml. ICC/IF: 1:100 - 1:1000. IHC-P: 1:50-1:200. IHC-Fr: 1:50-1:200. ChIP assay: 1-3 µl. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein G Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 4°C, -80°C |
| UniProt Number | Q60591 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
