Article No
GTX17816
Specifications
| Application | IHC |
| Article No | GTX17816 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | STAT6/2410 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | STAT6 antibody [STAT6/2410] |
| Supplier | GeneTex |
| Entrez Gene ID | 6778 |
| Gene Symbol | STAT6 |
| Immunogen | Recombinant full-length human STAT6 protein |
| Isotype | IgG1 |
| Notes | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Product Type | Antibodies Primary |
| Protocol | IHC-P: 1-2µg/ml for 30 min at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein A/G Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P42226 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
