Article No
GTX17119
Specifications
| Application | IHC |
| Article No | GTX17119 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 1F8 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Rb antibody [1F8] (ready-to-use) |
| Supplier | GeneTex |
| Entrez Gene ID | 5925 |
| Gene Symbol | RB1 |
| Immunogen | Recombinant human Rb protein. |
| Isotype | IgG1 |
| Notes | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
| Product Type | Antibodies Primary |
| Protocol | IHC-P: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Purified |
| Size | 6ml |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P06400 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
