Article No
CSB-PA950615-50
Specifications
| Application | ELISA, IHC, WB |
| Article No | CSB-PA950615-50 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | MAPK10 Antibody |
| Supplier | Cusabio |
| Entrez Gene ID | 5602 |
| Gene Symbol | MAPK10 |
| Immunogen | Synthetic peptide of Human MAPK10 |
| Isotype | IgG |
| Notes | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Shipping Information | BLUE ICE |
| Size | 50ul |
| Source / Host | rabbit |
| Species Reactivity | human, mouse, rat |
| Storage | -80°C |
| UniProt Number | P53779 |
| Product Page Updated | 2024-01-24T14:15:14.857Z |
