Article No
CHI-HF-211B7H3B-C100
B7-H3(4Ig) [B7-H3b] (human):Fc (mouse) (rec.)
B7-H3(4Ig) [B7-H3b] (human):Fc (mouse) (rec.)
Proteins & Peptides
Specifications
| MW | ~100kDa (SDS-PAGE) |
| Accession Number | NP_001019907.1 |
| Article No | CHI-HF-211B7H3B-C100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | B7-H3(4Ig) [B7-H3b] (human):Fc (mouse) (rec.) |
| Supplier | Adipogen Life Sciences |
| Endotoxin | <5EU/mg protein (LAL test; Lonza). |
| Format | Powder |
| Notes | B7-H3(4Ig) or B7-H3b has two additional Ig-like domains (one V- type and one C- type) and shows a ubiquituous expression pattern. B7-H3(4Ig) is expressed on dendritic cells as well as activated T, B and NK cells. Human (4Ig) binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine release. It also seems to be required for late stage osteoblast differentiation.|Protein. The extracellular domain of human B7-H3(4Ig) [B7-H3b] (aa 27-461) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: 98% (SDS-PAGE). B7-H3(4Ig) or B7-H3b has two additional Ig-like domains (one V- type and one C- type) and shows a ubiquituous expression pattern. B7-H3(4Ig) is expressed on dendritic cells as well as activated T, B and NK cells. Human (4Ig) binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine release. It also seems to be required for late stage osteoblast differentiation. |
| Product Type | Proteins & Peptides |
| Purity | >98% |
| Research area | Immunology |
| Sequence | The extracellular domain of human B7-H3(4Ig) [B7-H3b] (aa 27-461) is fused to the N-terminus of the Fc region of mouse IgG2a. |
| Shipping Information | BLUE ICE |
| Size | 100 ug |
| Source / Host | human |
| Stability | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Lyophilized from 0.2µm-filtered solution in PBS. |
| Technical Specifications | Protein. The extracellular domain of human B7-H3(4Ig) [B7-H3b] (aa 27-461) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: 98% (SDS-PAGE). B7-H3(4Ig) or B7-H3b has two additional Ig-like domains (one V- type and one C- type) and shows a ubiquituous expression pattern. B7-H3(4Ig) is expressed on dendritic cells as well as activated T, B and NK cells. Human (4Ig) binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine release. It also seems to be required for late stage osteoblast differentiation. |
| UniProt Number | NP_001019907.1 |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
