Article No
BPS-79369
Specifications
| MW | 21 kDa |
| Additional Information | UBE2C or ubiquitin-conjugating enzyme E2C is a member of the E2 ubiquitin-conjugating enzyme family which is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C acted as a dominant-negative inhibitor which blocks the destruction of mitotic cyclins A and B and the onset of anaphase in frog embryos and mammalian cells. High UBE2C mRNA expression is associated with poor disease-free survival and overall survival. High tumor grade, as well as high Ki67 protein expression, was more frequent in the high-expression group of UBE2C. |
| Article No | BPS-79369 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | UBE2C, His-Tag Recombinant |
| Supplier | BPS Bioscience |
| Format | Aqueous buffer solution |
| Notes | Recombinant full-length Human UBE2C, also known as UBCH10. Genbank Accession No. NM_007019, with an N-terminal His-tag, expressed in E. coli. MW=21 kDa. |
| Alias Names | dJ447F3.2, UBCH10 |
| Shipping Information | -80°C (dry ice) |
| Size | 20 µg |
| Species Reactivity | human |
| Storage | At least 6 months at -70⁰C. Avoid freeze/thaw cycles. |
| Substrate / Buffer | 50 mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, and 25% glycerol. |
| UniProt Number | O00762 |
| Product Page Updated | 2024-04-26T09:56:27.777Z |
