Article No
BPS-30024
MW | 71.8 kDa |
Additional Information | PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN13 is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. PTPN13 binds to a negative regulatory domain in Fas that inhibits Fas-induced apoptosis. |
Article No | BPS-30024 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | Bas (PTPN13), GST-tag Recombinant |
Supplier | BPS Bioscience |
Format | Aqueous buffer solution |
Notes | Human, recombinant PTP-Bas, catalytic domain (Gene bank accession number NM_080685), a.a. 2091-2490 (catalytic domain), with N-terminal GST tag, MW=71.8 kDa, expressed in an E. coli expression system. |
Alias Names | Bas, FAP-1, PTPN13, APO-1/CD95-Associated Phosphatase 1, PTP-BAS, PNP1, PTP1E, PTPL1, PTPLE, PTP-BL, Fas-Associated Phosphatase 1 |
Product Type | Proteins & Peptides |
Shipping Information | -80°C (dry ice) |
Size | 50 µg |
Species Reactivity | human |
Storage | >12 months at -80°C |
Substrate / Buffer | 25 mM Tris-HCl, pH 8.0, 75 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, 10 mM glutathione. |
UniProt Number | Q12923 |
Product Page Updated | 2024-05-03T09:13:48.379Z |