Article No
Ab00777-10.6
alpha-2 integrin inserted-domain
Anti-alpha-2 integrin inserted-domain [2E10]
Antibodies Primary
Specifications
| Accession Number | P17301 |
| Additional Information | This is a recombinant monoclonal antibody. |
| Application | ELISA, FC |
| Article No | Ab00777-10.6 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 2E10 |
| Clone Type | recombinant |
| Conjugation | Unconjugated |
| Description | Anti-alpha-2 integrin inserted-domain [2E10] |
| Supplier | Absolute Antibody |
| Format | Purified |
| Isotype | Fab fragment |
| Notes | 2E10 was generated by immunizing BALB/c mice with a DNA vaccine containing the human alpha2 I-domain cDNAsequence within pVAC2. The alpha2 I-domain is expressed as a fusion protein with fragment C of tetanus toxoid (FrC-TT). The scFv was then created using a V-gene phage display library derived from RNA from mice splenocytes and isolated following selection on GST-I after 3 rounds of panning. |
| Alias Names | CD49b; alpha2-beta1 integrin; glycoprotein IaIIa; GP IaIIa; VLA2; VLA-2; collagen receptor; alpha-2 integrin I-domain; integrin alpha-2; integrin alpha 2 |
| Product Type | Antibodies Primary |
| Purification | Purified |
| Shipping Information | Wet Ice |
| Size | 100 µg |
| Source / Host | human |
| Species Reactivity | human |
| Storage | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Substrate / Buffer | PBS with 0.02% Proclin 300. |
| Technical Specifications | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG (scFv) format, for improved compatibility with existing reagents, assays and techniques. |
| UniProt Number | P17301 |
| Product Page Updated | 2024-03-25T11:22:07.969Z |
