Article No
AT3868a
Accession Number | P78314 |
Application | WB, IF |
Article No | AT3868a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 1000000000 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | SH3BP2 Antibody |
Recommended Dilution | 1:500~1000 |
Supplier | Abgent |
Entrez Gene ID | 6452 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Isotype | IgG2a k |
Notes | The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Alias Names | SH3 domain-binding protein 2, 3BP-2, SH3BP2, 3BP2 |
Product Type | Antibodies Primary |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human |
Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Product Page Updated | 2023-11-23T13:40:12.472Z |