Article No
ASB-8OM045-0.1
Specifications
| NCBI Number | 12028, 24887, 581, 718948, 280730 |
| Application | WB, IP, FC, IHC, ICC, EM, Neutralization |
| Article No | ASB-8OM045-0.1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 6A7 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | Unconjugated |
| Description | Mouse Anti-Bax-UNLB |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Bax peptide (a.a. 12-24) common to mouse, rat, and human |
| Isotype | IgG1 |
| Notes | Bax is a 20-22 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. In murine thymocytes, it is expressed primarily as a cytoplasmic protein. Over-expression of Bax promotes apoptosis by formation of homodimers and through heterodimerization with Bcl-2, an inhibitor of apoptosis. The monoclonal antibody 6A7 reacts with human, mouse and rat Bax but does not bind the soluble cytosolic form of Bax; however, treatment of cells with non-ionic detergents exposes the epitope and allows binding of 6A7 to monomeric forms of Bax but not Bax complexed with either Bcl-2 or Bcl-xL. |
| Alias Names | Apoptosis regulator BAX, BCL2 associated X protein |
| Previous Article No | ASB-EG6CQS-0.1, ASB-1006001, ASB-8OM045-0.1 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 2-8°C |
| Substrate / Buffer | Borate buffered saline, pH 8.2 |
| Swiss-Prot No | Q07812, F6ZV96, Q8HYU5, O02703 |
| Product Page Updated | 2024-02-02T14:39:29.088Z |
| Volume | 1.0 mL |
