Article No
ASB-VLC1ML-0.1
NCBI Number | 12505 |
Application | FC |
Article No | ASB-VLC1ML-0.1 |
Biosite Brand | Biosite |
Country Availability | all |
Clone | KM201 |
Clone Type | monoclonal |
Concentration | 0.1 mg/mL |
Conjugation | Spectral Red |
Description | Rat Anti-Mouse CD44-SPRD |
Supplier | Nordic Biosite |
Format | Liquid |
Immunogen | (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2 |
Isotype | IgG1 |
Notes | CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells. |
Alias Names | Pgp-1, H-CAM, HUTCH-1, ECMR-III |
Previous Article No | ASB-AC6KQT-0.1, ASB-150013, ASB-VLC1ML-0.1 |
Product Type | Antibodies Primary |
Shipping Information | Ambient Temperature |
Size | 0.1 mg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | 2-8°C |
Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
Swiss-Prot No | P15379 |
Product Page Updated | 2024-01-11T10:51:07.446Z |
Volume | 1.0 mL |