Article No
ASB-OS4TRQ-0.1
NCBI Number | 12478 |
Application | FC |
Article No | ASB-OS4TRQ-0.1 |
Biosite Brand | Biosite |
Country Availability | all |
Clone | 6D5 |
Clone Type | monoclonal |
Concentration | 0.1 mg/mL |
Conjugation | PE/Cy7 |
Description | Rat Anti-Mouse CD19-PE/CY7 |
Supplier | Nordic Biosite |
Format | Liquid |
Immunogen | Mouse CD19-expressing K562 human erythroleukemia cells |
Isotype | IgG2a |
Notes | CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3. |
Alias Names | B4, Leu-12 |
Previous Article No | ASB-157517, ASB-OS4TRQ-0.1 |
Product Type | Antibodies Primary |
Shipping Information | Ambient Temperature |
Size | 0.1 mg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | 2-8°C |
Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
Swiss-Prot No | P25918 |
Product Page Updated | 2024-01-11T10:51:07.446Z |
Volume | 1.0 mL |