Article No
ASB-BHJ8XG-50
Mouse Anti-Human GSK-3β-SEPH
Mouse Anti-Human GSK-3β-SEPH
Antibodies Primary
Specifications
| NCBI Number | 2932 |
| Application | IP |
| Article No | ASB-BHJ8XG-50 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 5D6 |
| Clone Type | monoclonal |
| Concentration | Lot specific |
| Conjugation | SEPH |
| Description | Mouse Anti-Human GSK-3β-SEPH |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Recombinant N-terminal GSK-3beta |
| Isotype | IgG2b |
| Notes | Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 alpha and GSK-3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility. |
| Alias Names | Glycogen synthase kinase-3 |
| Previous Article No | ASB-IWYC24-50, ASB-1091525 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 50 tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 2-8°C |
| Substrate / Buffer | Borate buffered saline, pH 8.2 |
| Swiss-Prot No | P49841 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 2.0 mL |
