Article No
ARG21476
anti-IL10 antibody [JES5-2A5] (Biotin)
anti-IL10 antibody [JES5-2A5] (Biotin)
Antibodies Primary
Specifications
| MW | 21 kDa |
| Application | ELISA, ELISPOT, FC, IHC, Neutralization, WB |
| Article No | ARG21476 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | JES5-2A5 |
| Clone Type | monoclonal |
| Conjugation | Biotin |
| Description | anti-IL10 antibody [JES5-2A5] (Biotin) |
| Supplier | Arigo Biolaboratories Corporation |
| Immunogen | E. coli-expressed mouse IL-10 |
| Isotype | IgG1 k |
| Notes | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011] |
| Alias Names | IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10 |
| Product Type | Antibodies Primary |
| Size | 100 µg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Substrate / Buffer | PBS and 0.1% Sodium azide. |
| Swiss-Prot No | P18893 |
| Product Page Updated | 2023-12-01T13:07:23.905Z |
