Article No
ANC-267-820
anti-LTbetaR (human), mAb (ANCLTR2/9E2) (preservative free)
anti-LTbetaR (human), mAb (ANCLTR2/9E2) (preservative free)
Antibodies Primary
Specifications
| Application | ELISA, FC |
| Article No | ANC-267-820 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ANCLTR2/9E2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | anti-LTbetaR (human), mAb (ANCLTR2/9E2) (preservative free) |
| Supplier | Adipogen Life Sciences |
| Format | Liquid |
| Immunogen | Recombinant Human LT. |
| Isotype | IgG1 k |
| Notes | Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANCLTR2/9E2. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.|The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival. |
| Alias Names | Lymphotoxin-beta Receptor; Tumor Necrosis Factor Receptor 2 Related Protein; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor Superfamily Member 3; TNFRSF3 |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Storage | 4°C |
| Substrate / Buffer | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl |
| Technical Specifications | Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANCLTR2/9E2. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
