Article No
AMB-60IXF0-100
GRK2 Primary Antibody
GRK2 Primary Antibody
Antibodies Primary
Specifications
| MW | 80kDa |
| Application | WB, ELISA, ICC |
| Article No | AMB-60IXF0-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 3F8 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | GRK2 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 156 |
| Format | Ascitic fluid containing 0.03% sodium azide. |
| Immunogen | Purified recombinant fragment of human GRK2 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes |
| Alias Names | GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1 |
| Previous Article No | AMB-8636 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat, monkey |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
