Antibodies Primary

GRK2

NEW
Mouse Monoclonal Antibody to GRK2

Article No

AMB-8636

Application

ELISA, WB, IHC, ICC

Species Reactivity

human
mouse
rat
monkey

Size

100μl

Clone

3F8;

Source / Host

mouse

Suggested protocols

Specifications

MW 80kDa
Application ELISA, WB, IHC, ICC
Article No AMB-8636
BioSite Brand BioSite mAb
Clone 3F8;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to GRK2
Supplier BioSite Mab
Entrez Gene ID 156
Immunogen Purified recombinant fragment of human GRK2 expressed in E. Coli. ;
Isotype IgG1
Notes The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes
Alias Names GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size 100μl
Source / Host mouse
Species Reactivity human, mouse, rat, monkey
Storage 4°C -20°C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Product Page Updated 2019-08-02T12:49:54.081Z

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