GRK2

Article No AMB-8636
Product Type Antibodies Primary
Application ELISA, WB, IHC, ICC
Size 100μl

Specifications

MW 80kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 3F8;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to GRK2
Supplier BioSite Mab
Entrez Gene ID 156
Immunogen Purified recombinant fragment of human GRK2 expressed in E. Coli. ;
Isotype IgG1
Notes The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes
Alias Names GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Source / Host mouse
Species Reactivity human, mouse, rat, monkey
Storage 4 C, -20 C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human, mouse, rat, monkey human mouse rat monkey

Suggested protocols:

Western Blot

Western Blot

IHC-P

IHC-P