Article No
AM8516b-ev
Specifications
| MW | 58795 |
| Accession Number | O75030 |
| Application | WB |
| Article No | AM8516b-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1607CT834.207.47 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | MITF Antibody |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 4286 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Isotype | IgG1 k |
| Keywords | Crown Antibodies;Primary Antibodies;Immunology |
| Notes | Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. |
| Alias Names | Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, MITF, BHLHE32 |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Size | 50 µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Substrate / Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Technical Specifications | This MITF antibody is generated from a mouse immunized with a recombinant protein of human MITF. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
