Article No
AG-CN2-0103-MM25
CAS No | 29066-42-0 |
MW | 324.4 |
Article No | AG-CN2-0103-MM25 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | (R,R)-Hymeglusin |
Supplier | Adipogen Life Sciences |
Format | Powder |
Notes | beta-Lactone antibiotic [1]. Antibacterial and antifungal [1, 4]. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme [2-4, 6-8]. Mevalonate biosynthesis inhibitor [5].|Chemical. CAS: 29066-42-0. Formula: C18H28O5. MW: 324.4. Isolated from fungal strain Scopulariopsis sp. F-244. beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. |
Molecular Formula | C18H28O5 |
Alias Names | 1233A; F-244; L-659-699 |
Product Type | Chemicals & Biochemicals |
Purity | >95% |
Research area | Metabolism |
Shipping Information | RT |
Size | 2.5 mg |
Solubility | Soluble in methanol, ethanol, DMSO, chloroform or ethyl acetate. Insoluble in water or hexane. |
Stability | Stable for at least 3 years after receipt when stored at -20°C. |
Storage | -20°C, 4°C |
Technical Specifications | Chemical. CAS: 29066-42-0. Formula: C18H28O5. MW: 324.4. Isolated from fungal strain Scopulariopsis sp. F-244. beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. |
Product Page Updated | 2024-02-01T08:25:01.492Z |