Article No
AFC-5PFF06-0.1
Anti-AGR2/AGR3 Purified
Anti-AGR2/AGR3 Purified
Antibodies Primary
Specifications
| Application | WB, IHC, ICC |
| Article No | AFC-5PFF06-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | AGR3.4 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-AGR2/AGR3 Purified |
| Supplier | Nordic Biosite |
| Format | Purified |
| Immunogen | Purified human AGR3 protein |
| Isotype | IgG1 |
| Keywords | Serum & Plasma Proteins (Human) |
| Notes | AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development. |
| Alias Names | AG2, AG3, HAG2, HAG3 |
| Previous Article No | AFC-4442-2, AFC-5PFF06-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/ml; Positive tissue: human colon. Western blotting: Recommended dilution: 1 μg/ml; positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. Immunocytochemistry: Recommended dilution: 1 μg/ml; positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis. |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
