CD54

Article No AFC-5130-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, WB, IHC-P, ELISA
Size 100 tests

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone MEM-111
Clone Type monoclonal
Conjugation PE
Description Mouse Monoclonal to CD54 / ICAM-1
Recommended Dilution The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Supplier BioSite Flow
Immunogen Raji human Burkitt's lymphoma cell line
Isotype IgG2a
Keywords CD Antigens & MHC (Veterinary), CD and Related Antigens & MHC (Rodent), CD and Related Antigens (Human)
Notes CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. _x000D_
Species Reactivity rat, human, cow/bovine
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Substrate / Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Technical Specifications The antibody MEM-111 reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.<br><b>HLDA VI; WS Code AS A049</b>
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

rat, human, cow/bovine rat human

Suggested protocols:

Western Blot

Western Blot