Article No
AFC-E9GB7U-0.1
Application | FC |
Article No | AFC-E9GB7U-0.1 |
Biosite Brand | Biosite Flow |
Country Availability | all |
Clone | RB6-8C5 |
Clone Type | monoclonal |
Concentration | 0.5 mg/ml |
Conjugation | FITC |
Description | Anti-Ms Ly6G FITC |
Recommended Dilution | The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC. |
Supplier | Nordic Biosite |
Entrez Gene ID | 546644 |
Format | FITC |
Immunogen | Murine granulocytes |
Isotype | IgG2b |
Keywords | CD and Related Antigens & MHC (Rodent) |
Notes | Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses. |
Alias Names | Gr1, Gr-1, Ly-6G |
Previous Article No | AFC-5038-1, AFC-E9GB7U-0.1 |
Product Type | Antibodies Primary |
Protocol | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
Purification | Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
Research area | Immunology |
Size | 0.1 mg |
Source / Host | mouse |
Species Reactivity | mouse |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Technical Specifications | The rat monoclonal antibody RB6-8C5 detects Ly6G component of Gr-1 antigen, a commonly used surface marker of neutrophils. |
UniProt Number | A0A087WQF5 |
Product Page Updated | 2024-01-03T12:18:20.318Z |