Article No
AFC-UR1ANH-0.1
Anti-Lysozyme Purified
Anti-Lysozyme Purified
Antibodies Primary
Specifications
| Application | FC, ICC |
| Article No | AFC-UR1ANH-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | LZ598-10G9 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Lysozyme Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 4069 |
| Format | Purified |
| Immunogen | human lysozyme |
| Isotype | IgG1 |
| Keywords | Serum & Plasma Proteins (Human), CD and Related Antigens (Human) |
| Notes | Lysozyme is anti-bacterial enzyme found mainly in milk, saliva, tears, plasma, spleen, mucus, and leukocytes (e.g. in cytoplasmic granules of neutrophils). It damages bacterial cell walls by hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is part of the innate immune system. It protects wet body surfaces, such as conjunctiva. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. On the other hand high lysozyme blood levels produced for example by myelomonocytic leukemia cells can lead to kidney failure and low blood potassium. |
| Alias Names | LZM, LYZF1 |
| Previous Article No | AFC-4612-2, AFC-UR1ANH-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Intracellular staining; recommended dilution: 1-12 µg/ml. Excellent. Immunohistochemistry (paraffin sections): Positive tissue: tonsil. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The mouse monoclonal antibody LZ598-10G9 recognizes lysozyme, an approximately 17 kDa antibacterial enzyme, which is being used as a marker for the lineage diagnosis of acute leukemias (intracellular antigen). |
| UniProt Number | P61626 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
