Article No
AFC-1B9L4X-0.1
Anti-Hu CD328 Purified
Anti-Hu CD328 Purified
Antibodies Primary
Specifications
| Application | FC |
| Article No | AFC-1B9L4X-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | 6-434 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Hu CD328 Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 27036 |
| Format | Purified |
| Immunogen | human dendritic cells |
| Isotype | IgG1 |
| Keywords | CD and Related Antigens (Human) |
| Notes | CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells. |
| Alias Names | SIGLEC7, p75/AIRM1, D-siglec |
| Previous Article No | AFC-4611-2, AFC-1B9L4X-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 µg/ml |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The mouse monoclonal antibody 6-434 recognizes an extracellular epitope of CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes. |
| UniProt Number | Q9Y286 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
