Article No
AFC-HKBVVC-0.1
Anti-Ms CD41 Purified
Anti-Ms CD41 Purified
Antibodies Primary
Specifications
| Application | FC, IP, IHC, ELISA |
| Article No | AFC-HKBVVC-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | MWReg30 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Ms CD41 Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 16399 |
| Format | Purified |
| Immunogen | Murine platelets |
| Isotype | IgG1 k |
| Keywords | CD and Related Antigens & MHC (Rodent) |
| Notes | CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation. |
| Alias Names | Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GPIIb |
| Previous Article No | AFC-4593-2, AFC-HKBVVC-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
| Purification | Purified by protein-G affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | mouse |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The rat monoclonal antibody MWReg30 recognizes an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes. |
| UniProt Number | Q9QUM0 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
