Article No
AFC-VYGQ5M-0.1
Anti-Hu CD140b Purified
Anti-Hu CD140b Purified
Antibodies Primary
Specifications
| Application | FC, ICC |
| Article No | AFC-VYGQ5M-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | 18A2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Hu CD140b Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 5159 |
| Format | Purified |
| Immunogen | CD140b-transfected NIH 3T3 cells |
| Isotype | IgG1 |
| Keywords | Cytokine Signaling (Human), CD and Related Antigens (Human) |
| Notes | CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma. |
| Alias Names | PDGFRB, PDGFR1 |
| Previous Article No | AFC-4463-2, AFC-VYGQ5M-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Cell Signaling |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The monoclonal antibody 18A2 recognizes an extracellular epitope of CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles. |
| UniProt Number | Q59F04 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
