Article No
AFC-0G4W6I-0.1
Anti-HLA Class I Purified
Anti-HLA Class I Purified
Antibodies Primary
Specifications
| Application | FC, IP, ELISA |
| Article No | AFC-0G4W6I-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | MEM-123 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-HLA Class I Purified |
| Supplier | Nordic Biosite |
| Format | Purified |
| Immunogen | COS-7 African green monkey kidney cells |
| Isotype | IgG3 |
| Keywords | CD Antigens & MHC (Veterinary), MHC (Major Histocompatibility Complex) and Related Antigens (Human) |
| Notes | HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules. |
| Previous Article No | AFC-4285-2, AFC-0G4W6I-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 4 μg/ml. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | cow/bovine, human, monkey |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide |
| Technical Specifications | The antibody MEM-123 reacts with an extracellular epitope of all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9. |
| Product Page Updated | 2024-04-17T07:49:05.048Z |
