HLA-Class I

Article No AFC-4285-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, ELISA
Size 0.1 mg


Country Availability all
BioSite Brand BioSite Flow
Clone MEM-123
Clone Type monoclonal
Concentration 1 mg/ml
Conjugation Unconjugated
Description Mouse Monoclonal to HLA-Class I
Supplier BioSite Flow
Immunogen COS-7 African green monkey kidney cells
Isotype IgG3
Keywords CD Antigens & MHC (Veterinary), MHC (Major Histocompatibility Complex) and Related Antigens (Human)
Notes HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Purification Purified by protein-A affinity chromatography
Purity > 95% (by SDS-PAGE)
Species Reactivity human, monkey, cow/bovine
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The antibody MEM-123 reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types.<br> The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9.
Product Page Updated 2018-07-27T09:12:01.609Z

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Species reactivity:

human, monkey, cow/bovine human monkey

Suggested protocols: