Article No
A65921-050
ATG4D Polyclonal Antibody, Biotin Conjugated
ATG4D Polyclonal Antibody, Biotin Conjugated
Antibodies Primary
Specifications
| Application | ELISA |
| Article No | A65921-050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | Biotin |
| Description | ATG4D Polyclonal Antibody, Biotin Conjugated |
| Supplier | Epigentek |
| Format | Protein G Purified |
| Immunogen | Recombinant Human Cysteine protease ATG4D protein (14-43AA) |
| Isotype | IgG |
| Keywords | Apoptosis & Cell Death |
| Notes | Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. |
| Alias Names | Cysteine protease ATG4D, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, ATG4D, APG4D, AUTL4 |
| Product Type | Antibodies Primary |
| Purity | Protein G purified |
| Research area | Cell Death |
| Size | 50 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| UniProt Number | Q86TL0 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
