Article No
A55827-050
Dio3 Polyclonal Antibody, HRP Conjugated
Dio3 Polyclonal Antibody, HRP Conjugated
Antibodies Primary
Specifications
| Application | ELISA |
| Article No | A55827-050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | HRP |
| Description | Dio3 Polyclonal Antibody, HRP Conjugated |
| Supplier | Epigentek |
| Immunogen | Recombinant Rat Thyroxine 5-deiodinase protein (37-278AA) |
| Isotype | IgG |
| Keywords | Cell Metabolism |
| Notes | Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development. _x000D_ |
| Alias Names | 5DIII, DIOIII, Type 3 DI, Type-III 5'-deiodinase, Dio3, Itdi3, Txdi3 |
| Product Type | Antibodies Primary |
| Purity | Protein G purified |
| Research area | Metabolism |
| Size | 50 µl |
| Source / Host | rabbit |
| Species Reactivity | rat |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| UniProt Number | P49897 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
