Disintegrin EC3B Polyclonal Antibody, HRP Conjugated

Disintegrin EC3B Polyclonal Antibody, HRP Conjugated

Antibodies Primary

Article No

A54973-050

Application

ELISA

Species Reactivity

other vertebrates

Size

50 µl

Source / Host

rabbit

Article No

A54973-050

Application

ELISA

Species Reactivity

other vertebrates

Size

50 µl

Source / Host

rabbit

Specifications

Application ELISA
Article No A54973-050
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, GL
Clone Type polyclonal
Conjugation HRP
Description Disintegrin EC3B Polyclonal Antibody, HRP Conjugated
Supplier Epigentek
Immunogen Recombinant Echis carinatus Disintegrin EC3B protein (1-67AA)
Isotype IgG
Keywords Cellular Structure
Notes Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.
Alias Names Disintegrin EC3B
Product Type Antibodies Primary
Purity Protein G purified
Research area Cell Signaling
Size 50 µl
Source / Host rabbit
Species Reactivity other vertebrates
Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Substrate / Buffer 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
UniProt Number P81631
Product Page Updated 2024-02-13T10:42:34.821Z

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