Article No
A300-014A-T
CSN5
Rabbit anti-CSN5 Antibody, Affinity Purified
Antibodies Primary
Specifications
| Accession Number | NP_006828.2 |
| Application | IHC, WB |
| Article No | A300-014A-T |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | 1000 ug/ml |
| Conjugation | Unconjugated |
| Description | Rabbit anti-CSN5 Antibody, Affinity Purified |
| Recommended Dilution | IHC 1:250 - 1:2000, WB 1:5000 - 1:25000 |
| Supplier | Bethyl Laboratories |
| Entrez Gene ID | 10987 |
| Format | Whole IgG |
| Gene Symbol | COPS5 |
| Immunogen | Between 175 and 225 |
| Isotype | IgG |
| Notes | Rabbit anti-CSN5 Antibody, Affinity Purified |
| Alias Names | 38 kDa Mov34 homolog, COP9 constitutive photomorphogenic homolog subunit 5, COP9 signalosome complex subunit 5, CSN5, JAB1, jun activation domain-binding protein 1, MOV-34, SGN5, signalosome subunit 5, testis secretory sperm-binding protein Li 231m |
| Predicted Species Reactivity | frog, zebrafish |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Size | 10 µl |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Stability | 1 year from date of receipt |
| Storage | 4°C |
| Substrate / Buffer | Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide |
| Technical Specifications | CSN5 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN also possesses kinase activity. CSN5 has been identified as the subunit that functions to remove Nedd8, an ubiquitin-like modifier, from cullin-based E3-ubiquitin ligases. CSN5 also functions as a coactivator of nuclear receptors. COP9 signalsome complex subunit 5, signalsome subunit 5, SGN5, jun activation domain-protein 1, COPS5, JAB1, MOV-34, MGC3149. |
| UniProt Number | Q92905 |
| Product Page Updated | 2024-05-10T09:29:25.715Z |
| Volume | 10 µl |
