Article No
42-1474-200
HSP47
Anti-HSP47 Monoclonal Antibody (Clone : 1C4-1A6) - ATTO 594
Antibodies Primary
Specifications
| Application | ICC, IF, WB |
| Article No | 42-1474-200 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 1C4-1A6 |
| Clone Type | monoclonal |
| Conjugation | ATTO 594 |
| Description | Anti-HSP47 Monoclonal Antibody (Clone : 1C4-1A6) - ATTO 594 |
| Supplier | Abeomics |
| Entrez Gene ID | 871 |
| Gene Symbol | SERPINH1 |
| Immunogen | Human HSP47, full length |
| Isotype | IgG1 k |
| Notes | HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils. |
| Alias Names | SERPINH1||CBP1||CBP2||HSP47||SERPINH2||PIG14 |
| Product Type | Antibodies Primary |
| Protocol | WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user. |
| Purification | Protein G Purified |
| Shipping Information | Blue Ice |
| Size | 200 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| UniProt Number | P50454 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
