Article No
36-2245-0.5
Application | IHC |
Article No | 36-2245-0.5 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 1D5 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-Estrogen Receptor, alpha (Marker of Estrogen Dependence) Monoclonal Antibody(Clone: 1D5) |
Supplier | Abeomics |
Entrez Gene ID | 2099 |
Gene Symbol | ESR1 |
Immunogen | Recombinant human Estrogen Receptor alpha protein |
Isotype | IgG1 k |
Notes | This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas. |
Alias Names | Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 +49 isoform; Nuclear receptor subfamily 3 group A member 1 |
Product Type | Antibodies Primary |
Protocol | Immunohistochemistry (Formalin-fixed) (1:100-1:200 for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
Shipping Information | Blue Ice |
Size | 0.5 ml |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Substrate / Buffer | Tissue culture supernatant with 0.05% Azide. Contact us if you require it in a different format. |
UniProt Number | P03372 |
Product Page Updated | 2024-02-06T07:35:53.072Z |