Article No
36-1615-100
CD45 / LCA (Leucocyte Marker)
Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(Clone : 2B11)
Antibodies Primary
Specifications
| Application | FC, IF, IHC |
| Article No | 36-1615-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 2B11 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(Clone : 2B11) |
| Supplier | Abeomics |
| Entrez Gene ID | 5788 |
| Gene Symbol | PTPRC |
| Immunogen | Isolated neoplastic cells from T cell lymphoma |
| Isotype | IgG1 k |
| Keywords | Antibodies, Cancer Marker, CD45 / LCA (Leucocyte Marker), PTPRC, 5788, P08575, PTPRC, CD45, 2B11, Isolated neoplastic cells from T cell lymphoma, Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(Clone : 2B11), Antibody to CD45 / LCA (Leucocyte Marker), Anti-CD45 / LCA (Leucocyte Marker) Antibody, CD45 / LCA (Leucocyte Marker) Antibody |
| Notes | CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. |
| Alias Names | PTPRC||CD45 |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Affinity Purified |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P08575 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
