Article No
303-OIgY-1000
Application | IHC |
Article No | 303-OIgY-1000 |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Concentration | See vial for concentration. |
Description | Normal Ostrich IgY (egg-derived) |
Supplier | Exalpha Biologicals |
Format | Liquid |
Immunogen | Purified rabbit skeletal muscle actin |
Notes | The antibody 5C5 which is directed against sarcomeric alpha-actin labels skeletal and heart muscle cells but not smooth muscle cells. In neoplasms it may be used as a marker of rhabdomyosarcoma. Movement of cell organelles, cells, and organisms depends on the interaction of the cytoskeletal proteins actin and myosin. In birds and mammals up to now six different isoforms of actin have been identified using amino acid sequence analysis and electrophoresis. They are more or less specific for different organs resp. cell types. Four isoforms are known to occur in muscle cells, while two other forms are found in most other cell types. Alpha-Actin sarcomeric (a-sr-1) specific for skeletal- and heart-muscle. |
Product Type | Antibodies Isotype Control |
Protocol | (RTU) neat |
Purification | Egg yolk-derived purified IgY (non affinity purified) |
Shipping Information | The antibody is shipped at ambient temperature. |
Size | 1000 mg |
Source / Host | bird/avian |
Storage | The antibody may be stored at +4°C. For prolonged storage prepare appropriate aliquots and store at -20°C. Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day. An aliquot should be thawed slowly at ambient temperature and centrifuged to remove precipitate. This may result in a thin lipid layer floating on top and/or a visible precipitate. Removal of either will not affect the performance or the concentration of the product. |
Substrate / Buffer | Phosphate buffered saline with 0.075% sodium azide |
Technical Specifications | Optimal working dilutions should be determined for your particular assay conditions. |
UniProt Number | P68133 (ACTS_HUMAN) |
Product Page Updated | 2023-12-29T14:25:47.027Z |