Article No
30-2392-100
CD154 / CD40L
Anti-CD154 / CD40L Monoclonal Antibody (Clone:24-31)-PE Conjugated
Antibodies Primary
Specifications
| Application | FA, FC, ICC |
| Article No | 30-2392-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 24-31 |
| Clone Type | monoclonal |
| Conjugation | PE |
| Description | Anti-CD154 / CD40L Monoclonal Antibody (Clone:24-31)-PE Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 959 |
| Gene Symbol | CD40LG |
| Immunogen | human CD154 fusion protein |
| Isotype | IgG1 |
| Notes | CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center. |
| Alias Names | CD40LG||CD40L||TNFSF5||TRAP |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 100 Tests |
| Source / Host | mouse |
| Species Reactivity | human, monkey |
| Storage | 4°C |
| UniProt Number | P29965 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
