Article No
30-1313-0.1
CD105 / Endoglin
Anti-CD105 / Endoglin Monoclonal Antibody (Clone:MEM-229)
Antibodies Primary
Specifications
| Application | FC, ICC, IHC, WB |
| Article No | 30-1313-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MEM-229 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD105 / Endoglin Monoclonal Antibody (Clone:MEM-229) |
| Supplier | Abeomics |
| Entrez Gene ID | 2022 |
| Gene Symbol | ENG |
| Immunogen | Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA. |
| Isotype | IgG2a |
| Notes | CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels. |
| Alias Names | ENG||END |
| Product Type | Antibodies Primary |
| Purification | Protein A Purified |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human, pig/porcine |
| Storage | 4°C |
| UniProt Number | P17813 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
