Article No
246-X1018XS
Mouse anti Phosphotyrosine, conjugated with peroxidase
Mouse anti Phosphotyrosine, conjugated with peroxidase
Antibodies Primary
Specifications
| Additional Information | Please note: Minimum order quantity 2 items |
| Application | WB, IP, IHC |
| Article No | 246-X1018XS |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | PY20 |
| Clone Type | monoclonal |
| Concentration | See vial for concentration |
| Conjugation | HRP |
| Description | Mouse anti Phosphotyrosine, conjugated with peroxidase |
| Supplier | Nordic - MUbio |
| Immunogen | Hybridoma produced from Balb/C mice immunized with phosphotyrosine coupled to carrier protein. |
| Isotype | IgG2b |
| Notes | The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years, While the phosphorylation of specific tyrosine residues has be shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved invaluable to the study of tyrosine-phosphorylated proteins and the biochemical pathways in which they fuction. The HRP conjugate of PY20 anti-phosphotyrosine is especailly useful for the detection of phosphotyrosyl proteins in western blotting, immunohistochemical and immuncytochemical protcols in situations wherin the use of a secondary antibody would produce undesirable background signals. |
| Alias Names | Mouse anti phosphotyrosine, PY20, HRP conjugate, Horseradish peroxidase conjugate |
| Previous Article No | 246-X1018XS |
| Product Type | Antibodies Primary |
| Protocol | Working dilution of 1:2,000 is suggested for western blot or ELISA, 1:500 for immunohistochemistry or immunocytochemistry. |
| Purification | Prot A/G |
| Shipping Information | Ship at ambient temperature |
| Size | 50 µg |
| Source / Host | mouse |
| Species Reactivity | multi species |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Product Page Updated | 2024-02-15T14:19:39.649Z |
