Article No
182-HM2030-20UG
IP-10, Human, mAb 6D4 – 20 µg
IP-10, Human, mAb 6D4 – 20 µg
Antibodies Primary
Specifications
| Application | FC, IA, IF, WB |
| Article No | 182-HM2030-20UG |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Clone | 6D4 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | IP-10, Human, mAb 6D4 – 20 µg |
| Supplier | Hycult biotechnology |
| Format | 0.2 ml (100 μg/ml) 0.2 μm filtered protein G purified antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide. |
| Immunogen | Recombinant human IP-10 |
| Isotype | IgG2a |
| Notes | The monoclonal antibody 6D4 recognizes human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids. IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFNɣ inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation. |
| Alias Names | 10 kDa interferon gamma-induced protein, CXCL10, Small-inducible cytokine B10 Gene name: CXCL10 |
| Previous Article No | 182-HM2030-20UG, HM2030-20UG |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | Room Temperature |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label. |
| Substrate / Buffer | Quantities >500 µg will be send without preservative and carrier free. Quantities |
| Product Page Updated | 2024-04-05T09:42:44.568Z |
