Article No
155-99-308
NCBI Number | 403158 |
Application | Cell Separation, FC, IHC, IP, WB |
Article No | 155-99-308 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | EP72 |
Clone Type | monoclonal |
Concentration | 0.5 mg/ml |
Conjugation | Biotin |
Description | CD8a Antibody [EP72] (Biotin) |
Supplier | ProSci |
Entrez Gene ID | 403158 |
Format | Liquid |
Gene Symbol | CD8A |
Immunogen | Chicken splenocytes |
Isotype | IgG2b |
Notes | In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8alpha- and CD8beta-chains, a relatively large proportion of the CD8+ TCRgammadelta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRgammadelta CD8alphabeta cells in the chicken that is not found in rodents. The monoclonal antibody EP72 recognizes the CD8alpha chain. |
Previous Article No | 155-99-308-0.5 |
Product Type | Antibodies Primary |
Protocol | CD8a Antibody [EP72] for use in flow cytometry and immunohistochemistry assays. |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.5 mg |
Source / Host | mouse |
Species Reactivity | chicken |
Storage | 4°C |
Substrate / Buffer | Supplied in PBS/NaN3 |
Technical Specifications | CD8a Antibody [EP72] for use in flow cytometry and immunohistochemistry assays. |
Product Page Updated | 2024-01-03T13:34:25.701Z |