Article No
155-98-991
NCBI Number | 12520 |
Accession Number | P35762 |
Application | Cell Separation, FC, IHC, IP, WB |
Article No | 155-98-991 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 2F7 |
Clone Type | monoclonal |
Concentration | 0.5 mg/ml |
Conjugation | FITC |
Description | CD81 Antibody [2F7] (FITC) |
Supplier | ProSci |
Entrez Gene ID | 12520 |
Format | Liquid |
Gene Symbol | Cd81 |
Immunogen | Mouse epithelial cell line PAM212 |
Isotype | IgG |
Notes | CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gammadelta+ T cells to more mature T cells with alphabeta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pTalpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro. |
Alias Names | TAPA-1 |
Previous Article No | 155-98-991-0.5 |
Product Type | Antibodies Primary |
Protocol | CD81 Antibody [2F7] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays. |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.5 mg |
Source / Host | hamster |
Species Reactivity | mouse |
Storage | 4°C |
Substrate / Buffer | Supplied in PBS/NaN3 |
Technical Specifications | CD81 Antibody [2F7] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays. |
UniProt Number | P35762 |
Product Page Updated | 2024-01-03T13:34:25.701Z |