Article No
155-98-946
NCBI Number | 16637 |
Accession Number | Q60653 |
Application | Cell Separation, FC, IHC, IP |
Article No | 155-98-946 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | HBF-719 |
Clone Type | monoclonal |
Concentration | 0.5 mg/ml |
Conjugation | Unconjugated |
Description | Ly-49F Antibody [HBF-719] |
Supplier | ProSci |
Entrez Gene ID | 16637 |
Format | Liquid |
Gene Symbol | Klra6 |
Immunogen | CHO-K1 cells transfected with B6 allele of Ly49F gene |
Isotype | IgG1 |
Notes | The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains ~11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice. |
Alias Names | Ly-49 |
Previous Article No | 155-98-946-0.5 |
Product Type | Antibodies Primary |
Protocol | Ly-49F Antibody [HBF-719] for use in flow cytometry assays. |
Research area | Immunology |
Shipping Information | DRY ICE |
Size | 0.5 mg |
Source / Host | mouse |
Species Reactivity | mouse |
Storage | -20°C |
Substrate / Buffer | Supplied in PBS |
Technical Specifications | Ly-49F Antibody [HBF-719] for use in flow cytometry assays. |
UniProt Number | Q60653 |
Product Page Updated | 2024-01-03T13:34:25.701Z |